The legalization and commercialization of marijuana edibles in the U.S. reportedly has coincided with an escalation in cannabis-related poisonings.

More than 22,000 cannabis-related incidents were reported to poison control centers last year, according to data from America’s Poison Centers (APC). In 2009, only 930 such incidents were reported.

Among last year’s reported incidents, 13,000 caused documented negative effects and were classified as nonlethal poisonings, The New York Times reported Sunday.

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